Job Details

Who We Are

BioMarin Pharmaceutical Inc. is a company founded in 1997 and based in San Rafael, CA that specializes in the development of therapeutics for serious and often times life‑threatening rare diseases, in which a core component of products is enzyme replacement therapies. To date, it has become the first company to commercialize treatments for types of mucopolysaccharidosis (MPS) and phenylketonuria (PKU). The Quality Control Process Monitoring group is a laboratory that works in tandem with Manufacturing suites of the Novato, CA production facility which evaluates how well all major stages meet respective characteristic and performance parameters to ensure consistency and quality of each final product line.

This a contract role: Shift 4x10 Sunday-Wednesday but may change due to business need (Shifts are Sunday-Wednesday Day (0700-1800) /Swing (1300-0000) or Wednesday-Saturday Day (0700-1800) /Swing (1300-0000) Pay rate up to $27 per hour.

Job Description

The Quality Control Analytical In-Process (QCA-IP) Analyst is responsible for performing analytical test methods on in-process intermediates and varying stages of drug products under minimal supervision and within cGMP guidelines, to support further manufacturing of commercial and clinical therapeutics. This role will involve knowledge that includes but is not limited to the following analyses and concepts: Protein determination by A280, Bradford, and UV Absorbance, Enzyme activity, HPLC/UPLC, and method validation. Functional activities may include: performing a wide variety of analytical assays, maintaining test sample throughput, monitoring lab supplies, preparing reagents, contributing to process and method validation studies, supporting investigations and equipment validation, and brainstorming further development or improvement ideas for procedures. Employee is expected to follow SOPs, make appropriate decisions in daily activities with minimal needs for intervention, and be able to recognize deviations from routine practices. Incumbent must accurately complete tasks on time to achieve lab goals, meanwhile limiting GMP / procedural errors, and be capable of accepting and incorporating feedback. Must also demonstrate the ability to both manage time and prioritize routine work effectively.

Responsibilities

• 1. Timely facilitation of incoming sample receipt and accessioning flow, decipher batch assignments across all assay types in accordance with agreed upon best practices.
• 2. Execute analytical methods to facilitate in-process testing under applicable cGMP guidelines, as well as contribute to the prompt reporting of results to meet the required timetables of internal customers.
• 3. Evaluate completed assay validity, calculate and summarize results, analyze data per expected or specification ranges. Assist with the compilation and verification of trend analysis reports.
• 4. Perform and collaborate with co-workers to appropriately share general housekeeping activity assignments and ensure systems for laboratory maintenance are adequate for creating a consistent state of inspection readiness.
• 5. Assist with monitoring and the control of laboratory supply and critical reagent inventories.
• 6. Qualify as trainer for specified methods, provide training to less experienced staff.
• 7. Exhibit proactive communication upon occurrence of compliance risks and deviations from laboratory procedures, perform initiation of investigation records within required timeframes.
• 8. Provide input or assay support to the progression of test method validation, investigations, technical studies, and method transfer protocols.
• 9. Attend team huddles and department meetings, generate ideas for laboratory infrastructure improvements and method optimization.
• 10. Perform other responsibilities as deemed necessary.

Qualifications

• 1. Bachelor of Science degree.
• 2. 0-3 years of relevant laboratory experience; QC specific experience is preferred.
• 3. Experience with quality management systems, current Good Manufacturing Practices, and QC principles.
• 4. Demonstrated working knowledge with respect to certified functional activities.
• 5. Good documentation, written and verbal communication skills are essential.
• 6. Must possess the ability to perform most tasks with minimal supervision.
• 7. Computer literacy is required, with proficiency in Microsoft Word and Excel, and experience in Microsoft PowerPoint preferred.
• 8. Must have a quality service attitude and focus, exhibit flexibility and willingness to work additional hours to meet production or laboratory process requirements.

Note

Note: This description is not intended to be all-inclusive, or a limitation of the duties of the position. It is intended to describe the general nature of the job that may include other duties as assumed or assigned.

Equal Opportunity Employer

Equal Opportunity Employer/Veterans/Disabled
An Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability.